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Randomized Phase II Study of Talazoparib Versus Talazoparib Plus Atezolizumab After Palbociclib Combination Endocrine Therapy for Patients With Premenopausal HR+/HER2- Metastatic Breast Cancer Harboring HRD Scar

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Trial Profile

Randomized Phase II Study of Talazoparib Versus Talazoparib Plus Atezolizumab After Palbociclib Combination Endocrine Therapy for Patients With Premenopausal HR+/HER2- Metastatic Breast Cancer Harboring HRD Scar

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 12 Feb 2024

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At a glance

  • Drugs Atezolizumab (Primary) ; LHRH receptor agonists (Primary) ; Palbociclib (Primary) ; Talazoparib (Primary)
  • Indications Advanced breast cancer; HER2 negative breast cancer
  • Focus Therapeutic Use
  • Acronyms Young-PALETTA
  • Most Recent Events

    • 09 Dec 2023 Trial design, presented at the 46th Annual San Antonio Breast Cancer Symposium
    • 26 Jul 2021 Planned number of patients changed from 180 to 178.
    • 01 Apr 2021 New trial record
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