A Randomized, Double-Blinded, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Efficacy of IMB-1018972 in Patients With Non-obstructive Hypertrophic Cardiomyopathy
Latest Information Update: 25 Apr 2024
At a glance
- Drugs Ninerafaxstat (Primary)
 - Indications Hypertrophic cardiomyopathy
 - Focus Adverse reactions; Proof of concept
 - Acronyms IMPROVE-HCM
 - Sponsors Imbria Pharmaceuticals
 
Most Recent Events
- 22 Apr 2024 Status changed from active, no longer recruiting to completed.
 - 08 Apr 2024 According to an Imbria Pharmaceuticals media release, results from this trial support initiation of the Phase 3 FORTITUDE-HCM clinical trial of ninerafaxstat in patients with symptomatic non-obstructive hypertrophic cardiomyopathy (nHCM).
 - 08 Apr 2024 According to an Imbria Pharmaceuticals media release, results from the Phase 2 IMPROVE-HCM clinical trial were presented in a late-breaking clinical trial session at the American College of Cardiology Annual Scientific Session & Expo (ACC.24) and published in the Journal of the American College of Cardiology (JACC).