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A randomized, three-phase crossover study evaluating the pharmacokinetic interaction of atorvastatin and fixed-dose combination of sofosbuvir/ledipasvir in healthy male Egyptian volunteers

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Trial Profile

A randomized, three-phase crossover study evaluating the pharmacokinetic interaction of atorvastatin and fixed-dose combination of sofosbuvir/ledipasvir in healthy male Egyptian volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Apr 2021

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At a glance

  • Drugs Atorvastatin (Primary) ; Ledipasvir/sofosbuvir (Primary) ; Ledipasvir; Paracetamol; Sofosbuvir
  • Indications Cardiovascular disorders; Heart failure; Hepatic-porphyria; Hepatitis B; Hepatitis C; Hypercholesterolaemia; Hyperlipoproteinaemia type IIa; Hyperlipoproteinaemia type III; Hypertriglyceridaemia; Low HDL cholesterol
  • Focus Adverse reactions; Pharmacokinetics

Most Recent Events

  • 07 Apr 2021 New trial record
  • 01 Apr 2021 Results published in the European Journal of Clinical Pharmacology

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