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A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors

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Trial Profile

A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 28 Aug 2024

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At a glance

  • Drugs Berzosertib (Primary) ; Sacituzumab govitecan (Primary)
  • Indications Neuroendocrine tumours; Prostate cancer; Small cell lung cancer; Solid tumours
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 05 Aug 2024 Status changed from suspended to recruiting.
    • 04 Jun 2024 Status changed from recruiting to suspended. (Placed on hold for interim study review/assessment.)
    • 25 May 2024 Planned number of patients changed from 85 to 120.

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