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A Multicentre, Open-label, Dose-escalating, Phase Ib, Study of Intravenous Dosing of NG-641, as Monotherapy or in Combination With Pembrolizumab in Patients With Surgically Resectable Squamous Cell Carcinoma of the Head and Neck

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Trial Profile

A Multicentre, Open-label, Dose-escalating, Phase Ib, Study of Intravenous Dosing of NG-641, as Monotherapy or in Combination With Pembrolizumab in Patients With Surgically Resectable Squamous Cell Carcinoma of the Head and Neck

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 26 Mar 2025

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At a glance

  • Drugs NG 641 (Primary) ; Pembrolizumab (Primary)
  • Indications Head and neck cancer; Hypopharyngeal cancer; Laryngeal cancer; Mouth neoplasm; Oropharyngeal cancer; Squamous cell cancer
  • Focus Adverse reactions
  • Acronyms MOAT
  • Sponsors Akamis Bio

Most Recent Events

  • 24 Mar 2025 Status changed from active, no longer recruiting to completed.
  • 08 Aug 2024 Status changed from recruiting to active, no longer recruiting.
  • 21 Jun 2023 Planned End Date changed from 1 Dec 2023 to 1 Oct 2024.

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