Trial Profile

A Phase I/II Randomized, Double-blind, Placebo-controlled Trial (1-BETTER) Examining XB2001 (Anti-IL-1⍺ True Human Antibody) in Combination With ONIVYDE + 5-FU/LV (+Folinic Acid) in Advanced Pancreatic Cancer

Status: Completed

Phase of Trial: Phase I/II

Latest Information Update: 07 Aug 2026

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At a glance

Drugs Fluorouracil (Primary) ; Folinic acid (Primary) ; Irinotecan (Primary) ; Vilamakitug (Primary)
Indications Adenocarcinoma; Pancreatic cancer
Focus Adverse reactions
Acronyms 1-BETTER
Sponsors XBiotech

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