A Phase Ib, Open-Label, Multicenter Study to Evaluate the Safety, Pharmacokinetics, and Activity of Belvarafenib as a Single Agent and in Combination With Either Cobimetinib or Cobimetinib Plus Nivolumab in Patients With NRAS-Mutant Advanced Melanoma Who Have Received Anti-PD-1/PD-L1 Therapy
Latest Information Update: 13 Oct 2025
At a glance
- Drugs Belvarafenib (Primary) ; Cobimetinib (Primary) ; Nivolumab (Primary)
- Indications Malignant melanoma; Skin cancer
- Focus Adverse reactions
- Sponsors Genentech
Most Recent Events
- 30 Sep 2025 Planned End Date changed from 28 Nov 2025 to 31 Dec 2025.
- 30 Sep 2025 Planned primary completion date changed from 28 Nov 2025 to 31 Dec 2025.
- 15 Feb 2024 Status changed from recruiting to active, no longer recruiting.