Trial Profile

A Phase II Study of NirAparib, Dostarlimab and Radiotherapy in Metastatic, PD-L1 Negative or Immunotherapy-Refractory Triple-Negative Breast Cancer (NADiR)

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 13 Oct 2025

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At a glance

Drugs Dostarlimab (Primary) ; Niraparib (Primary)
Indications Advanced breast cancer; HER2 negative breast cancer; Male breast cancer; Triple negative breast cancer
Focus Therapeutic Use
Acronyms NADiR

Most Recent Events

01 Oct 2025 Planned primary completion date changed from 1 Apr 2025 to 1 Feb 2027.
01 Oct 2025 Status changed from recruiting to active, no longer recruiting.
13 Nov 2023 Planned primary completion date changed from 1 Apr 2023 to 1 Apr 2025.

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