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An observational, retrospective, case series study of factor VIII inhibitor bypassing activity (FEIBA) for factor Xa (FXa) inhibitor reversal for apixaban and rivaroxaban in patients with acute intracranial and nonintracranial hemorrhage

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Trial Profile

An observational, retrospective, case series study of factor VIII inhibitor bypassing activity (FEIBA) for factor Xa (FXa) inhibitor reversal for apixaban and rivaroxaban in patients with acute intracranial and nonintracranial hemorrhage

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 15 Apr 2021

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At a glance

  • Drugs Factor VIII inhibitor bypassing fraction (Primary)
  • Indications Haemophilia; Intracranial haemorrhages
  • Focus Therapeutic Use
  • Most Recent Events

    • 15 Apr 2021 New trial record
    • 10 Apr 2021 Primary endpoint (effectiveness of FEIBA to achieve excellent or good (collectively defined as effective) hemostasis for acute ICH and non-ICH bleeding events secondary to apixaban or rivaroxaban at the doses utilized) has not been met.
    • 10 Apr 2021 Results published in the Annals of Pharmacotherapy

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