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Evaluation of Effectiveness of KDR2-2 Suspension Eyedrop on Neovascular Regression in the Treatment of Neovascular Glaucoma: an Exploratory Clinical Trial

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Trial Profile

Evaluation of Effectiveness of KDR2-2 Suspension Eyedrop on Neovascular Regression in the Treatment of Neovascular Glaucoma: an Exploratory Clinical Trial

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 04 Jan 2024

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At a glance

  • Drugs KDR2-2 (Primary)
  • Indications Neovascular glaucoma
  • Focus Therapeutic Use
  • Acronyms KDR-NVG
  • Most Recent Events

    • 04 Jan 2022 Phase amended from II to I. Study design changed from parallel, nonrandomized to single group assignment. 16mg/ml group and 4mg/ml group are merged into single arm. Time frame of primary outcome changed from Day 0, 7, 14, 21 and 28 to Day 0 and 7. In other outcomes, new measure "Changes of iris neovascularization" added and "Corneal endothelium count and Changes of anterior chamber structures" are removed, time frame changed from Day 0, 1, 7, 14, 21 and 28 to Day 0, 7 and 28.
    • 04 Jan 2022 Planned primary completion date changed from 31 Dec 2021 to 31 Jan 2022.
    • 01 Sep 2021 Planned number of patients changed from 20 to 40.

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