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Phase I Open Label, Drug-Drug Interaction, Study to Evaluate the Effect of Itraconazole and Phenytoin on the Pharmacokinetics of ASC41 in Healthy Volunteers and A Study to Evaluate the PK, Safety and Tolerability in Subjects With Non-alcoholic Fatty Liver Disease (NAFLD).

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Trial Profile

Phase I Open Label, Drug-Drug Interaction, Study to Evaluate the Effect of Itraconazole and Phenytoin on the Pharmacokinetics of ASC41 in Healthy Volunteers and A Study to Evaluate the PK, Safety and Tolerability in Subjects With Non-alcoholic Fatty Liver Disease (NAFLD).

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 28 Dec 2023

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At a glance

  • Drugs ASC 41 (Primary) ; Itraconazole; Phenytoin
  • Indications Non-alcoholic fatty liver disease
  • Focus Pharmacokinetics
  • Sponsors Gannex Pharma

    • Most Recent Events

    • 14 Nov 2023 Results assessing safety, tolerability, PK and PD of single and multiple ascending oral doses of ASC41 in Two Phase 1 Studies NCT04527250 & NCT04845646, presented at The Liver Meeting 2023: 74th Annual Meeting of the American Association for the Study of Liver Diseases.
    • 13 Nov 2023 Results presented in an Ascletis Media Release
    • 13 Nov 2023 According to an Ascletis media release, data from this study will be presented at the Liver Meeting 2023 of the American Association for the Study of Liver Diseases (AASLD).

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