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A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study Comparing the Efficacy and Safety of Tirzepatide Versus Placebo in Patients With Heart Failure With Preserved Ejection Fraction and Obesity (SUMMIT)

Trial Profile

A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study Comparing the Efficacy and Safety of Tirzepatide Versus Placebo in Patients With Heart Failure With Preserved Ejection Fraction and Obesity (SUMMIT)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 17 Mar 2025

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At a glance

  • Drugs Tirzepatide (Primary)
  • Indications Heart failure; Obesity
  • Focus Registrational; Therapeutic Use
  • Acronyms SUMMIT
  • Sponsors Eli Lilly and Company

Most Recent Events

  • 01 Feb 2025 Results of mechanistic secondary analysis from SUMMIT trial were published in the Nature Medicine.
  • 16 Nov 2024 Results presented in an Eli Lilly and Company Media Release.
  • 16 Nov 2024 According to an Eli Lilly and Company media release, company submitted tirzepatide for the treatment of HFpEF and obesity to the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) and plans to submit to other regulatory agencies starting later this year.

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