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A Pilot Phase I Trial of IL-21 Expanded, Off the Shelf, Third-Party Natural Killer (NK) Cells in Combination With Mogamulizumab in Patients With Cutaneous T-Cell Lymphomas or Adult T-Cell Leukemia/Lymphomas

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A Pilot Phase I Trial of IL-21 Expanded, Off the Shelf, Third-Party Natural Killer (NK) Cells in Combination With Mogamulizumab in Patients With Cutaneous T-Cell Lymphomas or Adult T-Cell Leukemia/Lymphomas

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 05 Feb 2024

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At a glance

  • Drugs Cyclophosphamide (Primary) ; Fludarabine (Primary) ; Mogamulizumab (Primary) ; Natural killer cell therapy (Primary)
  • Indications Adult T-cell leukaemia-lymphoma; Cutaneous T-cell lymphoma
  • Focus Adverse reactions

    • Most Recent Events

    • 30 Jan 2024 Planned primary completion date changed from 31 Dec 2023 to 31 Dec 2024.
    • 14 Dec 2021 Trial design presented at the 63rd American Society of Hematology Annual Meeting and Exposition
    • 27 Sep 2021 Planned initiation date (estimated date for recruitment of the first subject) changed from 1 Jun 2021 to 1 Nov 2021.

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