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A Double-Blind, Placebo-Controlled, Randomized, Multipart, Single and Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered JNJ-75220795

Trial Profile

A Double-Blind, Placebo-Controlled, Randomized, Multipart, Single and Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered JNJ-75220795

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 24 Jan 2025

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At a glance

  • Drugs ARO PNPLA3 (Primary)
  • Indications Non-alcoholic fatty liver disease
  • Focus Adverse reactions; First in man
  • Sponsors Janssen Research & Development

Most Recent Events

  • 16 Aug 2023 Status changed from recruiting to completed.
  • 28 Feb 2023 Planned primary completion date changed from 2 Nov 2022 to 11 Jan 2024.
  • 15 Feb 2023 According to a Arrowhead Pharmaceuticals Media Release, the company has gained rights to ARO-PNPLA3 which was part of a 2018 research collaboration and option agreement between Arrowhead and Janssen Pharmaceuticals.

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