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An Open-label Study to Evaluate the Impact of Acid-reducing Agents on the Pharmacokinetics of AMG 510 in Healthy Subjects Under Fed Conditions

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Trial Profile

An Open-label Study to Evaluate the Impact of Acid-reducing Agents on the Pharmacokinetics of AMG 510 in Healthy Subjects Under Fed Conditions

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 03 Nov 2022

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At a glance

  • Drugs Famotidine (Primary) ; Omeprazole (Primary) ; Sotorasib (Primary)
  • Indications Brain metastases; Colorectal cancer; Non-small cell lung cancer; Pancreatic cancer; Solid tumours
  • Focus Pharmacokinetics

    • Most Recent Events

    • 21 Apr 2021 New trial record
    • 17 Mar 2021 Results presented at the 122nd Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics

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