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A Phase II, Double-blind, Placebo-controlled, Randomized, Dose-ranging, Parallel Group Study to Evaluate the Safety and Efficacy of PHA-022121 Administered Orally for Prophylaxis Against Angioedema Attacks in Patients With Hereditary Angioedema Due to C1-Inhibitor Deficiency (Type I or Type II)

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Trial Profile

A Phase II, Double-blind, Placebo-controlled, Randomized, Dose-ranging, Parallel Group Study to Evaluate the Safety and Efficacy of PHA-022121 Administered Orally for Prophylaxis Against Angioedema Attacks in Patients With Hereditary Angioedema Due to C1-Inhibitor Deficiency (Type I or Type II)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 06 Sep 2024

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At a glance

  • Drugs Deucrictibant (Primary)
  • Indications Hereditary angioedema
  • Focus Proof of concept; Therapeutic Use
  • Acronyms CHAPTER-1; HAE CHAPTER-1
  • Sponsors Pharvaris
  • Most Recent Events

    • 05 Sep 2024 According to a Pharvaris media release, data from this study will be presented at the Bradykinin Symposium in Dallas, TX from September 13-14, 2024
    • 28 Aug 2024 According to a Pharvaris media release, data from this study will be presented at the upcoming 7th Bradykinin Symposium, to be held from September 5-6, 2024, in Berlin, Germany.
    • 04 Jun 2024 According to a Pharvaris media release, data from this study presented at the European Academy of Allergy and Clinical Immunology (EAACI) Congress 2024.

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