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A Phase II, Double-blind, Placebo-controlled, Randomized, Dose-ranging, Parallel Group Study to Evaluate the Safety and Efficacy of PHA-022121 Administered Orally for Prophylaxis Against Angioedema Attacks in Patients With Hereditary Angioedema Due to C1-Inhibitor Deficiency (Type I or Type II)

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Trial Profile

A Phase II, Double-blind, Placebo-controlled, Randomized, Dose-ranging, Parallel Group Study to Evaluate the Safety and Efficacy of PHA-022121 Administered Orally for Prophylaxis Against Angioedema Attacks in Patients With Hereditary Angioedema Due to C1-Inhibitor Deficiency (Type I or Type II)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 16 May 2024

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At a glance

  • Drugs Deucrictibant (Primary)
  • Indications Hereditary angioedema
  • Focus Proof of concept; Therapeutic Use
  • Acronyms CHAPTER-1; HAE CHAPTER-1
  • Sponsors Pharvaris
  • Most Recent Events

    • 13 May 2024 According to a Pharvaris media release, company announced the acceptance of abstracts for presentation at the 20th Annual Congress of International Drug Discovery Science and Technology (IDDST); the 2024 Eastern Allergy Conference (EAC); and the European Academy of Allergy and Clinical Immunology (EAACI) Congress 2024.
    • 04 Apr 2024 According to a Pharvaris media release, efficacy and safety results from this trial will be presented at the Consortium of Independent Immunology Clinics (CIIC) Spring 2024 Conference, to be held from April 12-13, 2024, in Arlington, TX.
    • 18 Mar 2024 According to a Pharvaris media release, quality of life data were presented at the ITACA meeting
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