Trial Profile

A Phase Ib Trial of Zanubrutinib in Combination With R-PolaCHP (ZaR-PolaCHP) for Patients With Newly Diagnosed Diffuse Large B-Cell Lymphoma

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 10 Dec 2025

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At a glance

Drugs Zanubrutinib (Primary) ; Cyclophosphamide; Doxorubicin; Prednisone; Rituximab; Vincristine
Indications Diffuse large B cell lymphoma
Focus Adverse reactions

Most Recent Events

24 Nov 2025 Planned number of patients changed from 24 to 38.
24 Nov 2025 Planned End Date changed from 15 Oct 2025 to 15 Jun 2026.
24 Nov 2025 Planned primary completion date changed from 15 Oct 2025 to 15 May 2026.

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