A Phase 1/2, Open-label, Dose-exploration and Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NTX-301 Monotherapy in Advanced Solid Tumours, and in Combination With Platinum-based Chemotherapy in Advanced Ovarian & Bladder Cancer, and in Combination With Temozolomide as Adjuvant (Maintenance) Therapy in High-grade Glioma (Optional Arm)
Latest Information Update: 22 Dec 2022
At a glance
- Drugs NTX-301 (Primary) ; Carboplatin; Cisplatin; Temozolomide
- Indications Bladder cancer; Glioblastoma; Glioma; Ovarian cancer; Solid tumours
- Focus Adverse reactions
- Sponsors Pinotbio; Xennials Therapeutics
- 18 Dec 2022 Status changed from recruiting to discontinued.
- 02 Sep 2021 According to a Xennials Therapeutics media release, first patient have been dosed in this study.
- 12 Jul 2021 Status changed from not yet recruiting to recruiting.