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A Phase 2 Open-Label Multicenter Study to Evaluate the Safety and Efficacy of Selinexor With or Without Pembrolizumab Versus Standard of Care in Previously Treated Metastatic Colorectal Cancer With RAS Mutations

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Trial Profile

A Phase 2 Open-Label Multicenter Study to Evaluate the Safety and Efficacy of Selinexor With or Without Pembrolizumab Versus Standard of Care in Previously Treated Metastatic Colorectal Cancer With RAS Mutations

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 07 Nov 2023

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At a glance

  • Drugs Pembrolizumab (Primary) ; Selinexor (Primary) ; Tipiracil/trifluridine
  • Indications Colorectal cancer
  • Focus Therapeutic Use
  • Sponsors Karyopharm Therapeutics

    • Most Recent Events

    • 12 Sep 2022 Status changed from active, no longer recruiting to discontinued.
    • 02 Jun 2022 Planned primary completion date changed from 1 Apr 2022 to 1 Jul 2022.
    • 02 Jun 2022 Status changed from recruiting to active, no longer recruiting.

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