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A Multicentric Phase 2 Study of Venetoclax and Azacitidine for the Management of Molecular Relapse/Progression in Adult NPM1-MUTATED Acute Myeloid Leukemia

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Trial Profile

A Multicentric Phase 2 Study of Venetoclax and Azacitidine for the Management of Molecular Relapse/Progression in Adult NPM1-MUTATED Acute Myeloid Leukemia

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 09 Jan 2023

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At a glance

  • Drugs Venetoclax (Primary) ; Azacitidine; Azacitidine
  • Indications Acute myeloid leukaemia
  • Focus Therapeutic Use
  • Acronyms AML2521

    • Most Recent Events

    • 13 Dec 2022 Results (n=9) characterizing a series of NPM1-Mutated Acute Myeloid Leukemia pts in molecular failure who received VEN-AZA as bridge-to-transplant treatment strategy presented at the 64th American Society of Hematology Annual Meeting and Exposition
    • 01 Mar 2022 Status changed from not yet recruiting to recruiting.
    • 31 Dec 2021 Planned End Date changed from 1 Sep 2024 to 1 Jan 2025.
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