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A study to assess whether FOLFIRI plus aflibercept has efficacy following FOLFOXIRI plus Bevacizumab treatment

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A study to assess whether FOLFIRI plus aflibercept has efficacy following FOLFOXIRI plus Bevacizumab treatment

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 14 Oct 2024

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At a glance

  • Drugs Aflibercept (Primary) ; Fluorouracil; Irinotecan; Levofolinic acid
  • Indications Adenocarcinoma; Colon cancer; Colorectal cancer; Rectal cancer
  • Focus Therapeutic Use
  • Acronyms EFFORT study

    • Most Recent Events

    • 06 Jun 2023 Status changed to completed according to Results presented at the 59th Annual Meeting of the American Society of Clinical Oncology.
    • 06 Jun 2023 Primary endpoint(progression-free survival (PFS) has been met according to Results presented at the 59th Annual Meeting of the American Society of Clinical Oncology.
    • 06 Jun 2023 Results (n=34) assessing safety and efficacy of FOLFIRI plus aflibercept as second-line treatment after failure of FOLFOXIRI plus bevacizumab in patients with unresectable/metastatic colorectal cancer presented at the 59th Annual Meeting of the American Society of Clinical Oncology

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