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A Phase 2, Multicenter, Randomized, Double-blind, Placebo Controlled Study to Assess the Safety, Pharmacokinetics, and Efficacy of KPL-404 in Subjects With Moderate to Severe Active Rheumatoid Arthritis With Inadequate Response or Intolerance to at Least One Biologic Disease-modifying Anti-rheumatic Drug or a Janus Kinase Inhibitor

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A Phase 2, Multicenter, Randomized, Double-blind, Placebo Controlled Study to Assess the Safety, Pharmacokinetics, and Efficacy of KPL-404 in Subjects With Moderate to Severe Active Rheumatoid Arthritis With Inadequate Response or Intolerance to at Least One Biologic Disease-modifying Anti-rheumatic Drug or a Janus Kinase Inhibitor

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 31 Jul 2024

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At a glance

  • Drugs Abiprubart (Primary)
  • Indications Rheumatoid arthritis
  • Focus Adverse reactions; Pharmacokinetics; Proof of concept; Therapeutic Use
  • Sponsors Kiniksa Pharmaceuticals

    • Most Recent Events

    • 15 Jun 2024 Results evaluating the safety and PK of multiple SC doses of abiprubart , presented at the 25th Annual Congress of the European League Against Rheumatism
    • 14 Jun 2024 This trial has been completed in Bulgarian, according to the European Clinical Trials Database record.
    • 06 Jun 2024 Status changed from active, no longer recruiting to completed.

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