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An Open Label, Single-arm, Phase 2 Study of Neoadjuvant Nivolumab and Nab-paclitaxel Before Radical Cystectomy for Patients With Muscle-invasive Bladder Cancer

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Trial Profile

An Open Label, Single-arm, Phase 2 Study of Neoadjuvant Nivolumab and Nab-paclitaxel Before Radical Cystectomy for Patients With Muscle-invasive Bladder Cancer

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 05 Mar 2024

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At a glance

  • Drugs Nivolumab (Primary) ; Paclitaxel (Primary)
  • Indications Bladder cancer; Carcinoma; Urogenital cancer
  • Focus Therapeutic Use
  • Acronyms NURE-Combo
  • Most Recent Events

    • 27 Jan 2024 First results (n=31) assessing safety and efficacy of neoadjuvant nivolumab (NIVO) and nab-paclitaxel (ABX) followed by postsurgical adjuvant NIVO in patients (pts) with muscle-invasive bladder cancer presented at the 2024 Genitourinary Cancers Symposium
    • 06 Jun 2023 Results (between 02/17 and 08/18, n=115) presented at the 59th Annual Meeting of the American Society of Clinical Oncology
    • 03 Mar 2022 Status changed from not yet recruiting to recruiting.
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