Trial Profile

An Open-label, Phase 1, Dose-escalation Study to Evaluate the Safety and Preliminary Antitumor Activity of TAK-676 With Pembrolizumab Following Radiation Therapy in the Treatment of Non-small-cell Lung Cancer, Triple-negative Breast Cancer, or Squamous-cell Carcinoma of the Head and Neck That Has Progressed on Checkpoint Inhibitors

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 07 Sep 2025

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At a glance

Drugs Dazostinag (Primary) ; Pembrolizumab (Primary)
Indications Advanced breast cancer; Carcinoma; Head and neck cancer; Male breast cancer; Non-small cell lung cancer; Squamous cell cancer; Triple negative breast cancer
Focus Adverse reactions
Sponsors Takeda

10 Jun 2024 Status changed from active, no longer recruiting to completed.
22 Mar 2024 Planned End Date changed from 18 Feb 2024 to 1 May 2024.
22 Mar 2024 Planned primary completion date changed from 18 Feb 2024 to 1 May 2024.

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