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A Phase 1/2, Randomized, Observer-Blinded Study to Evaluate the Safety and Immunogenicity of a Quadrivalent Hemagglutinin Nanoparticle Influenza and SARS-CoV-2 rS Nanoparticle Combination Vaccine With Matrix M1 Adjuvant in Healthy Participants ≥ 50 to ≤ 70 Years of Age

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Trial Profile

A Phase 1/2, Randomized, Observer-Blinded Study to Evaluate the Safety and Immunogenicity of a Quadrivalent Hemagglutinin Nanoparticle Influenza and SARS-CoV-2 rS Nanoparticle Combination Vaccine With Matrix M1 Adjuvant in Healthy Participants ≥ 50 to ≤ 70 Years of Age

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 02 Feb 2023

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At a glance

  • Drugs COVID-19 vaccine adjuvanted Novavax (Primary) ; NanoFlu/NVX CoV 2373 combination vaccine-Novavax (Primary) ; Matrix-M1 Adjuvant
  • Indications COVID 2019 infections; Influenza virus infections
  • Focus Adverse reactions; Registrational
  • Sponsors Novavax

    • Most Recent Events

    • 23 Oct 2022 Preliminary safety, reactogenicity and immunogenicity results of COVID influenza combination vaccine in seropositive participants, presented at the IDWeek 2022.
    • 20 Oct 2022 According to a Novavax media release, new data from the trial will be presented at IDWeek 2022.
    • 13 Oct 2022 According to a Novavax media release, results from this trial were presented at the World Vaccine Congress (WVC) Europe 2022.

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