Phase I/II 225Ac-J591 Plus 177Lu-PSMA-I&T for Progressive Metastatic Castration Resistant Prostate Cancer
Latest Information Update: 23 Aug 2023
At a glance
- Drugs ATL 101 Telix Pharmaceuticals (Primary) ; Lutetium-177-PSMA-imaging-and-therapy (Primary)
- Indications Adenocarcinoma; Bone metastases; Liver metastases; Prostate cancer
- Focus Adverse reactions
- 15 Aug 2023 Planned number of patients changed from 33 to 48.
- 27 Jul 2023 Status changed from recruiting to suspended.
- 06 Jun 2023 Results (of phase I dose-escalation, n=18 ) assessing safety of of prostate-specific membrane antigen-targeted radionuclide therapy (PSMA-TRT) with alpha-radiolabeled antibody 225Ac-J591 and beta-radioligand 177Lu-PSMA I&T presented at the 59th Annual Meeting of the American Society of Clinical Oncology