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A Phase 1b-2, Multicenter, Trial to Evaluate the Efficacy, Safety, Pharmacokintetics, and Pharmacodynamics of REC-4881 in Patients with Familial Adenomatous Polyposis (FAP)

Trial Profile

A Phase 1b-2, Multicenter, Trial to Evaluate the Efficacy, Safety, Pharmacokintetics, and Pharmacodynamics of REC-4881 in Patients with Familial Adenomatous Polyposis (FAP)

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 08 May 2025

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At a glance

  • Drugs REC 4881 (Primary)
  • Indications Familial adenomatous polyposis
  • Focus Adverse reactions; Pharmacokinetics; Therapeutic Use
  • Acronyms TUPELO
  • Sponsors Recursion Pharmaceuticals

Most Recent Events

  • 04 May 2025 According to a Recursion Pharmaceuticals media release, preliminary results of this trial were presented in a late-breaking oral presentation at Digestive Disease Week (DDW) 2025 in San Diego, California.
  • 04 May 2025 Results presented in the Recursion Pharmaceuticals Media Release.
  • 27 Mar 2025 timeframe of primary endpoint changed of RP2D from 16 weeks to 27 months and Percent change from baseline in polyp burden from 12 weeks to 9weeks

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