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A Two-Part Study of REC-994 in the Treatment of Adults With Symptomatic Cerebral Cavernous Malformation (CCM); Part 1: A Phase 2 Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Evaluate the Safety, Efficacy and Pharmacokinetics of Two Doses of REC-994; Part 2: A Long-Term Blinded Extension Clinical Trial to Evaluate Long-Term Safety Tolerability and Efficacy of REC-994

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Trial Profile

A Two-Part Study of REC-994 in the Treatment of Adults With Symptomatic Cerebral Cavernous Malformation (CCM); Part 1: A Phase 2 Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Evaluate the Safety, Efficacy and Pharmacokinetics of Two Doses of REC-994; Part 2: A Long-Term Blinded Extension Clinical Trial to Evaluate Long-Term Safety Tolerability and Efficacy of REC-994

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 11 Feb 2025

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At a glance

  • Drugs Tempol (Primary)
  • Indications Central nervous system cavernous haemangioma
  • Focus Adverse reactions; Proof of concept
  • Acronyms SYCAMORE
  • Sponsors Recursion Pharmaceuticals

Most Recent Events

  • 05 Feb 2025 According to a Recursion Pharmaceuticals media release, Recursion will hold a webinar on Thursday, February 6th at 6:30am MT/8:30am ET/1:30pm GMT to present the Phase 2 data, Recursion intends to submit these data for publication in a peer reviewed scientific journal. Next steps will be guided by regulatory discussions and on-going long term extension study.
  • 05 Feb 2025 According to a Recursion Pharmaceuticals media release, results were presented today at the Late-Breaking Science Concurrent Oral Abstract Sessions at the International Stroke Conference (ISC) in Los Angeles, CA.
  • 05 Feb 2025 Results presented in the Recursion Pharmaceuticals Media Release

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