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A Phase Ib Study of Concurrent Chemoradiation in Combination With or Without PD1 Inhibitor AB122 Adenosine 2a Receptor / Adenosine 2b Receptor Inhibitor AB928 Therapies in Locally Advanced Head and Neck Cancers (PANTHEoN)

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Trial Profile

A Phase Ib Study of Concurrent Chemoradiation in Combination With or Without PD1 Inhibitor AB122 Adenosine 2a Receptor / Adenosine 2b Receptor Inhibitor AB928 Therapies in Locally Advanced Head and Neck Cancers (PANTHEoN)

Status: Withdrawn prior to enrolment
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2023

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At a glance

  • Drugs Etrumadenant (Primary) ; Zimberelimab (Primary) ; Cisplatin
  • Indications Head and neck cancer; Hypopharyngeal cancer; Laryngeal cancer; Oropharyngeal cancer; Pharyngeal neoplasms; Squamous cell cancer
  • Focus Adverse reactions; Pharmacodynamics
  • Acronyms PANTHEoN
  • Most Recent Events

    • 27 Oct 2023 Status changed from not yet recruiting to withdrawn prior to enrolment.
    • 25 Sep 2023 Planned End Date changed from 1 Aug 2025 to 1 Dec 2026.
    • 25 Sep 2023 Planned primary completion date changed from 1 Aug 2025 to 1 Dec 2025.

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