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A Phase 3, Randomized, Double-Blind, Placebo-Controlled Multicenter Study of Itolizumab in Combination With Corticosteroids for the Initial Treatment of Acute Graft Versus Host Disease

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Trial Profile

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Multicenter Study of Itolizumab in Combination With Corticosteroids for the Initial Treatment of Acute Graft Versus Host Disease

Status: Suspended
Phase of Trial: Phase III

Latest Information Update: 19 Nov 2024

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At a glance

  • Drugs Itolizumab (Primary) ; Corticosteroids
  • Indications Graft-versus-host disease
  • Focus Registrational; Therapeutic Use
  • Acronyms EQUATOR
  • Sponsors Equillium

    • Most Recent Events

    • 13 Nov 2024 According to an Equillium media release, the company to present an overview of the Company's clinical programs, currently focused on the Phase 3 EQUATOR study and the Phase 2 study of itolizumab in ulcerative colitis at the Stifel Healthcare Conference.
    • 31 Oct 2024 Status changed from recruiting to suspended, according to an Equillium media release.
    • 31 Oct 2024 According to an Equillium media release, to date company has enrolled over 150 patients and At this time, company is temporarily pausing enrollment to review clinical options for the program, including the potential to accelerate timeline to topline data to early 2025 while preserving registrational integrity of the study.

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