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A Phase 3, Randomized, Double-Blind, Placebo-Controlled Multicenter Study of Itolizumab in Combination With Corticosteroids for the Initial Treatment of Acute Graft Versus Host Disease

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Trial Profile

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Multicenter Study of Itolizumab in Combination With Corticosteroids for the Initial Treatment of Acute Graft Versus Host Disease

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 07 Oct 2024

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At a glance

  • Drugs Itolizumab (Primary) ; Corticosteroids
  • Indications Graft-versus-host disease
  • Focus Registrational; Therapeutic Use
  • Acronyms EQUATOR
  • Sponsors Equillium
  • Most Recent Events

    • 19 Aug 2024 Planned End Date changed from 1 Jul 2025 to 1 Dec 2025.
    • 19 Aug 2024 Planned primary completion date changed from 1 Jul 2024 to 1 Dec 2024.
    • 08 Aug 2024 According to an Equillium media release, company announced a positive interim review of the study by the Independent Data Monitoring Committee, which raised no safety or futility concerns and recommended that the study proceed as planned

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