Trial Profile

A Phase 2, Multicenter, Multi Arm, Study to Evaluate MK-1308A (Co-formulated Quavonlimab (MK-1308)/Pembrolizumab) Versus Other Treatments in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer: (MK-1308A-008)

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 09 Sep 2026

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At a glance

Drugs Favezelimab/pembrolizumab (Primary) ; MK-4830 (Primary) ; Pembrolizumab (Primary) ; Pembrolizumab+vibostolimab (Primary) ; Pembrolizumab/Quavonlimab (Primary)
Indications Adenocarcinoma; Colorectal cancer
Focus Therapeutic Use
Sponsors Merck Sharp & Dohme; Merck Sharp & Dohme Corp.

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