Trial Profile

A Global Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of mRNA-3705 in Participants With Isolated Methylmalonic Acidemia Due to Methylmalonyl-CoA Mutase Deficiency

Status: Discontinued

Phase of Trial: Phase I/II

Latest Information Update: 16 Jun 2026

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At a glance

16 Jun 2026 Last checked against Clinicaltrials.gov record.
06 May 2026 Status changed from active, no longer recruiting to discontinued.
02 Sep 2025 According to a Moderna media release, interim result data from this study have been accepted for presentation at the 2025 International Congress of Inborn Errors of Metabolism (ICIEM), which will be held September 2-6, 2025 in Kyoto, Japan, at the Kyoto International Conference Center.

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