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A Phase 1, Open-Label, Fixed Sequence, Drug-Drug Interaction Study to Evaluate the Effect of Inhibition of Uridine 5'-Diphosphate-glucuronosyltransferases (UGTs) on the Pharmacokinetics of Ecopipam Tablets and Its Active Metabolite (EBS-101-40853) in Healthy Subjects

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A Phase 1, Open-Label, Fixed Sequence, Drug-Drug Interaction Study to Evaluate the Effect of Inhibition of Uridine 5'-Diphosphate-glucuronosyltransferases (UGTs) on the Pharmacokinetics of Ecopipam Tablets and Its Active Metabolite (EBS-101-40853) in Healthy Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 02 May 2023

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At a glance

  • Drugs Ecopipam (Primary) ; Mefenamic acid (Primary) ; Valproate semisodium (Primary)
  • Indications Gilles de la Tourette's syndrome; Lesch-Nyhan syndrome; Restless legs syndrome; Speech disorders
  • Focus Pharmacokinetics
  • Sponsors Emalex Biosciences

    • Most Recent Events

    • 24 Mar 2023 Results assessing pharmacokinetics effects presented at the 124th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics
    • 20 Jul 2021 Status changed from recruiting to completed.
    • 31 May 2021 New trial record

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