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Defendor Special: A Multicenter Prospective Observational Post-registration Study of Combined Chemotherapy With Empegfilrastim Support to Evaluate Safety and Efficacy in Patients With High and "Gray Zone" Risk Reccurrence Breast Cancer, Gastointestinal Cancers and Gynecological Malignancies

Trial Profile

Defendor Special: A Multicenter Prospective Observational Post-registration Study of Combined Chemotherapy With Empegfilrastim Support to Evaluate Safety and Efficacy in Patients With High and "Gray Zone" Risk Reccurrence Breast Cancer, Gastointestinal Cancers and Gynecological Malignancies

Status: Recruiting
Phase of Trial: Phase IV

Latest Information Update: 09 Jun 2025

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At a glance

  • Drugs Empegfilgrastim (Primary) ; Carboplatin; Cyclophosphamide; Doxorubicin; Paclitaxel
  • Indications Febrile neutropenia
  • Focus Therapeutic Use
  • Acronyms Def_Special; Defendor Special

Most Recent Events

  • 30 Apr 2025 Results presented at the 116th Annual Meeting of the American Association for Cancer Research
  • 06 Jun 2023 Results of sub-group analysis evaluating the pCR after TCHP with PP by empegfilgrastim (E) or filgrastim (F) in patients with HER2+ eBC presented at the 59th Annual Meeting of the American Society of Clinical Oncology
  • 10 Dec 2022 Interim results (n=111; Data cutoff date: Apr 2020) presented at the 45th Annual San Antonio Breast Cancer Symposium

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