Trial Profile

A Randomized Clinical Trial of Ex Vivo Corneal Cross-Linking of Donor Keratoplasty Tissue for Keratoconus

Status: Not yet recruiting

Phase of Trial: Phase II

Latest Information Update: 22 Apr 2026

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At a glance

Drugs Riboflavin (Primary)
Indications Keratoconus
Focus Therapeutic Use
Acronyms EVOKE

Most Recent Events

08 Apr 2026 Planned initiation date changed from 1 Dec 2023 to 1 Jan 2027.
12 Jan 2023 According to ClinicalTrials.gov record, protocol has been amended to increase patient number from 10 to 216. Masking will be Double blind now instead of Open Label. Primary endpoint and number of arms are also changed, Randomization will be done.
12 Jan 2023 Planned number of patients changed from 10 to 216.

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