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A Multi-Center, Phase II Trial of HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide for Patients With Hematologic Malignancies

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Trial Profile

A Multi-Center, Phase II Trial of HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide for Patients With Hematologic Malignancies

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 05 Jan 2026

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At a glance

  • Drugs Busulfan (Primary) ; Busulfan (Primary) ; Fludarabine (Primary) ; Mesna (Primary) ; Cyclophosphamide; Mycophenolate mofetil; Mycophenolate mofetil; Tacrolimus; Tacrolimus
  • Indications Acute myeloid leukaemia; Graft-versus-host disease; Lymphoid leukaemia; Myelodysplastic syndromes
  • Focus Therapeutic Use
  • Acronyms ACCESS

Most Recent Events

  • 24 Nov 2025 According to a Dana-Farber Cancer Institute media release, data from this trial to be presented at ASH American Society of Hematology (ASH) 2025
  • 29 Jul 2025 Planned End Date changed from 1 Jul 2024 to 1 Dec 2025.
  • 29 Jul 2025 Planned primary completion date changed from 1 Jul 2024 to 1 Dec 2025.

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