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A Phase 1b Open-Label, Dose-Escalating Study to Evaluate the Safety and Tolerability of PLG0206 in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Occurring After Total Knee Arthroplasty (TKA)

Trial Profile

A Phase 1b Open-Label, Dose-Escalating Study to Evaluate the Safety and Tolerability of PLG0206 in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Occurring After Total Knee Arthroplasty (TKA)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 28 May 2025

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At a glance

  • Drugs PLG 0206 (Primary)
  • Indications Bone and joint infections
  • Focus Adverse reactions; Proof of concept
  • Acronyms LOGIC-1
  • Sponsors Peptilogics

Most Recent Events

  • 21 May 2025 Status changed from active, no longer recruiting to completed.
  • 19 Sep 2023 According to a Peptilogics media release, detailed analyses will be presented at various conferences in the coming months.
  • 19 Sep 2023 Top line interim results published in a Peptilogics Media Release

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