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A Multi-center, Prospective Randomized Controlled Trial on the Effects of Sacubitril-Valsartan vs Enalapril on Left Ventricular Remodeling in ST-elevation Myocardial Infarction

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Trial Profile

A Multi-center, Prospective Randomized Controlled Trial on the Effects of Sacubitril-Valsartan vs Enalapril on Left Ventricular Remodeling in ST-elevation Myocardial Infarction

Status: Not yet recruiting
Phase of Trial: Phase III

Latest Information Update: 25 Oct 2021

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At a glance

  • Drugs Sacubitril/valsartan (Primary) ; Valsartan (Primary) ; Enalapril
  • Indications Myocardial infarction
  • Focus Therapeutic Use
  • Acronyms PERI-STEMI

    • Most Recent Events

    • 20 Oct 2021 Planned End Date changed from 1 Jun 2026 to 1 Jun 2027, as per Trial design published in the Clinical Cardiology
    • 20 Oct 2021 Trial design, published in the Clinical Cardiology
    • 23 Sep 2021 Doses for active comparator Enalapril have been changed from 1.25 mg, 2.5 mg and 5 mg to 2.5 mg, 5 mg and 10 mg respectively.

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