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A Phase 2b Randomized, Double-Masked, Sham-Controlled, Study to Evaluate the Efficacy and Safety of Intravitreal Injection of MCO-010 Optogenetic Therapy in Adults With Retinitis Pigmentosa [RESTORE]

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Trial Profile

A Phase 2b Randomized, Double-Masked, Sham-Controlled, Study to Evaluate the Efficacy and Safety of Intravitreal Injection of MCO-010 Optogenetic Therapy in Adults With Retinitis Pigmentosa [RESTORE]

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 14 Jan 2026

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At a glance

  • Drugs Sonpiretigene isteparvovec (Primary)
  • Indications Retinitis pigmentosa
  • Focus Registrational; Therapeutic Use
  • Acronyms RESTORE
  • Sponsors Nanoscope Therapeutics

Most Recent Events

  • 05 Jan 2026 According to a Nanoscope Therapeutics media release, the initiation of the rolling BLA submission with the USFDA will be highlighted at the 44th Annual J.P. Morgan Healthcare Conference on Monday, January 12th, 2026 from 11:30 to 11:55 AM PST, by Sulagna Bhattacharya, Chief Executive Officer of the company.
  • 02 Dec 2025 According to a Nanoscope Therapeutics media release, data from this study will be presented at the FLORetina-ICOOR 2025 Congress, December 4th-7th at the Fortezza da Basso in Florence, Italy, by Dr. Jordi Mones and Dr. Allen C. Ho.
  • 26 Aug 2025 According to a Nanoscope Therapeutics media release, the company will present compelling new data from its RESTORE long-term follow-up study, REMAIN, at the 2025 Euretina Congress and Retina Society Annual Scientific Meeting

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