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A Multi-center, Open-label, Phase II Clinical Trial to Evaluate the Efficacy, Safety and Tolerability of Savolitinib in Treating Gastric Cancer and Esophagogastric Junction Adenocarcinoma Patients With MET Gene Amplifications

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Trial Profile

A Multi-center, Open-label, Phase II Clinical Trial to Evaluate the Efficacy, Safety and Tolerability of Savolitinib in Treating Gastric Cancer and Esophagogastric Junction Adenocarcinoma Patients With MET Gene Amplifications

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 22 May 2023

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At a glance

  • Drugs Savolitinib (Primary)
  • Indications Adenocarcinoma; Gastric cancer; Oesophageal cancer
  • Focus Registrational; Therapeutic Use
  • Sponsors Hutchison MediPharma; HUTCHMED

    • Most Recent Events

    • 19 Apr 2023 Results (n=20) assessing efficacy and safety from a phase 2 trial of savolitinib monotherapy in patients (pts) with MET-amplified advanced or metastatic GC/GEJ presented at the 114th Annual Meeting of the American Association for Cancer Research
    • 12 Apr 2023 According to a HUTCHMED media release, preliminary efficacy and safety data will be presented as a poster at American Association for Cancer Research Annual Meeting 2023 (AACR 2023), which will take place from April 14 to 19, 2023 in Orlando, Florida.
    • 04 Apr 2023 Planned number of patients changed from 75 to 135 as per HUTCHMED media release

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