A Phase 3 Randomized, Double-Blind, Decentralized Clinical Trial to Compare the Efficacy of Celiprolol to Placebo in the Treatment of Patients With COL3A1-Positive Vascular Ehlers-Danlos Syndrome
Latest Information Update: 15 May 2025
At a glance
- Drugs Celiprolol (Primary)
- Indications Ehlers-Danlos syndrome
- Focus Registrational; Therapeutic Use
- Acronyms DiSCOVER
- Sponsors Acer Therapeutics
Most Recent Events
- 08 May 2025 According to a Zevra Therapeutics media release, 5 additional patients enrolled in the Phase 3 DiSCOVER trial of celiprolol for the treatment of Vascular Ehlers-Danlos Syndrome, bringing the total number of enrolled patients to 32.
- 07 Apr 2025 According to a Zevra Therapeutics media release, company announced the closing of the sale of its Rare Pediatric Disease Priority Review Voucher (PRV) for gross proceeds of $150 million. The $150 million in gross proceeds is non-dilutive capital that will ongoing Phase 3 trial for celiprolol.
- 11 Mar 2025 According to a Zevra Therapeutics media release, as of Dec. 31, 2024, eight additional patients enrolled in the Phase 3 DiSCOVER trial of celiprolol for the treatment of Vascular Ehlers-Danlos Syndrome (VEDS), bringing the total patients enrolled to 27.