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A Phase 1b/2 Trial of Preoperative Niraparib, Dostarlimab, and Hypofractionated Radiotherapy for the Treatment of Locally-advanced Rectal Cancers

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A Phase 1b/2 Trial of Preoperative Niraparib, Dostarlimab, and Hypofractionated Radiotherapy for the Treatment of Locally-advanced Rectal Cancers

Status: Suspended
Phase of Trial: Phase I/II

Latest Information Update: 22 Nov 2024

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At a glance

  • Drugs Dostarlimab (Primary) ; Niraparib (Primary)
  • Indications Rectal cancer
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 19 Nov 2024 Planned End Date changed from 31 Dec 2026 to 31 Dec 2027.
    • 19 Nov 2024 Planned primary completion date changed from 31 Dec 2024 to 31 Dec 2025.
    • 19 Jul 2024 Status changed from recruiting to suspended.

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