Trial Profile

A Phase 1b/2 Trial of Preoperative Niraparib, Dostarlimab, and Hypofractionated Radiotherapy for the Treatment of Locally-advanced Rectal Cancers

Status: Discontinued

Phase of Trial: Phase I/II

Latest Information Update: 05 Mar 2025

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At a glance

Drugs Dostarlimab (Primary) ; Niraparib (Primary)
Indications Rectal cancer
Focus Adverse reactions; Therapeutic Use

Most Recent Events

27 Feb 2025 Status changed from suspended to discontinued.
19 Nov 2024 Planned End Date changed from 31 Dec 2026 to 31 Dec 2027.
19 Nov 2024 Planned primary completion date changed from 31 Dec 2024 to 31 Dec 2025.

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