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Prospective, randomized, open, multicenter Phase II trial to investigate the efficacy of trifluridine/tipiracil plus panitumumab versus trifluridine/tipiracil plus bevacizumab as first-line treatment of metastatic colorectal cancer: FIRE 8; AIO-KRK/YMO-0519

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Trial Profile

Prospective, randomized, open, multicenter Phase II trial to investigate the efficacy of trifluridine/tipiracil plus panitumumab versus trifluridine/tipiracil plus bevacizumab as first-line treatment of metastatic colorectal cancer: FIRE 8; AIO-KRK/YMO-0519

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 28 Mar 2024

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At a glance

  • Drugs Bevacizumab (Primary) ; Panitumumab (Primary) ; Tipiracil/trifluridine (Primary)
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Therapeutic Use
  • Acronyms AIO-KRK; FIRE-8; YMO-0519
  • Most Recent Events

    • 27 Jul 2022 Study design published in the BMC Cancer
    • 12 Aug 2021 Planned End Date changed from 15 Jun 2029 to 1 Dec 2032.
    • 21 Jun 2021 New trial record
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