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A Phase I/Ib Global, Multicenter, Open-label Umbrella Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

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Trial Profile

A Phase I/Ib Global, Multicenter, Open-label Umbrella Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 20 Dec 2024

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At a glance

  • Drugs Atezolizumab (Primary) ; Bevacizumab (Primary) ; Cetuximab (Primary) ; Inavolisib (Primary) ; SY 5609 (Primary) ; Tiragolumab (Primary)
  • Indications Adenocarcinoma; Colon cancer; Rectal cancer
  • Focus Therapeutic Use
  • Acronyms INTRINSIC
  • Sponsors Roche

    • Most Recent Events

    • 17 Dec 2024 Planned number of patients changed from 422 to 542.
    • 17 Dec 2024 Status changed from active, no longer recruiting to recruiting.
    • 26 Oct 2024 Planned End Date changed from 15 Apr 2026 to 7 Nov 2029.

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