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A Phase I/Ib Global, Multicenter, Open-label Umbrella Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

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Trial Profile

A Phase I/Ib Global, Multicenter, Open-label Umbrella Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 24 Jun 2024

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At a glance

  • Drugs Atezolizumab (Primary) ; Bevacizumab (Primary) ; Cetuximab (Primary) ; Inavolisib (Primary) ; SY 5609 (Primary) ; Tiragolumab (Primary)
  • Indications Adenocarcinoma; Colon cancer; Rectal cancer
  • Focus Therapeutic Use
  • Acronyms INTRINSIC
  • Sponsors Roche

    • Most Recent Events

    • 17 Jun 2024 Status changed from recruiting to active, no longer recruiting.
    • 01 Mar 2024 Planned End Date changed from 12 Aug 2026 to 15 Apr 2026.
    • 01 Mar 2024 Planned primary completion date changed from 12 Oct 2025 to 15 Sep 2025.

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