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Phase 1 investigator-initiated trial of eftilagimod alpha in conjunction with pembrolizumab plus doublet chemotherapy (carboplatin and pemetrexed) in patients with various solid tumors

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Trial Profile

Phase 1 investigator-initiated trial of eftilagimod alpha in conjunction with pembrolizumab plus doublet chemotherapy (carboplatin and pemetrexed) in patients with various solid tumors

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 06 Aug 2026

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At a glance

  • Drugs Carboplatin (Primary) ; Eftilagimod alpha (Primary) ; Pembrolizumab (Primary) ; Pemetrexed (Primary)
  • Indications Adenocarcinoma; Non-small cell lung cancer; Solid tumours
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Acronyms INSIGHT-003

Most Recent Events

  • 30 Jul 2026 Results presented in the Immutep media release.
  • 13 Jul 2026 Results (Data Cutoff 27 March 2026) presented in the Immutep Media Release
  • 29 Oct 2025 According to an Immutep Limited media release, data from this trial has been presented at ESMO 2025.

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