Phase 1 investigator-initiated trial of eftilagimod alpha in conjunction with pembrolizumab plus doublet chemotherapy (carboplatin and pemetrexed) in patients with various solid tuumours
Latest Information Update: 02 Aug 2024
At a glance
- Drugs Carboplatin (Primary) ; Eftilagimod alpha (Primary) ; Pembrolizumab (Primary) ; Pemetrexed (Primary)
- Indications Adenocarcinoma; Non-small cell lung cancer; Solid tumours
- Focus Adverse reactions; First in man; Therapeutic Use
- Acronyms INSIGHT-003
- 31 Jul 2024 According to an Immutep Limited media release, this trial continued to enrol patients throughout the quarter, with 43 out of a target of 50 patients enrolled and safely dosed across six sites in Germany. Further updates from INSIGHT-003 will be provided in CY2024.
- 29 Apr 2024 According to an Immutep Limited media release, 38 out of a total of 50 patients have been enrolled and safely dosed across six sites in Germany.
- 22 Nov 2023 According to an Immutep Limited media release, the extension opened in mid-2023 and 29 patients have been enrolled to date. With the addition of the new sites, the trial is expected to complete recruitment in 1H CY2024.