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Phase 1 investigator-initiated trial of eftilagimod alpha in conjunction with pembrolizumab plus doublet chemotherapy (carboplatin and pemetrexed) in patients with various solid tumors

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Trial Profile

Phase 1 investigator-initiated trial of eftilagimod alpha in conjunction with pembrolizumab plus doublet chemotherapy (carboplatin and pemetrexed) in patients with various solid tumors

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 21 May 2025

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At a glance

  • Drugs Carboplatin (Primary) ; Eftilagimod alpha (Primary) ; Pembrolizumab (Primary) ; Pemetrexed (Primary)
  • Indications Adenocarcinoma; Non-small cell lung cancer; Solid tumours
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Acronyms INSIGHT-003

Most Recent Events

  • 15 May 2025 Results (n=47) published in an Immutep Limited media release.
  • 29 Apr 2025 According to an Immutep Limited media release, Data updates from INSIGHT-003 are expected in CY2025.
  • 06 Jan 2025 According to an Immutep Limited media release, company announced that patient enrolment has been completed in this trial reached enrolment target of 50 patients.

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